하악골절 환자에서 악관절강내 활액의 PGE₂농도 분석
Analysis of PGE2 Concentration in Synovial Fluid Aspirates from TMJs of Patients with Mandibular Fracture
이기혁, 김현호, 정태영,
소속 상세정보
이기혁 ( ) - 조선대학교 치과대학 구강악안면외과학교실
김현호 ( ) - 조선대학교 치과대학 구강악안면외과학교실
정태영 ( ) - 조선대학교 치과대학 구강악안면외과학교실
KMID : 0353320010250010123
Abstract
The purpose of this study is to examine the change of enzymeimmuno-assay for prostaglandinE₂in the synovial fluid lavage specimen of patients with mandibular fracture patients without condylar fracture.
For this study, fourteen patients (eight males, six females) with mandibular fractures without condylar fracture was investigated to analyse the synovial fluid from upper temporomandibular joint cavities. Synovial fluid was collected from TMJ cavities of mandibular fracture patients before open reduction and after one week of open reduction, and then stored in liquid nitrogen tank after centrifuge. 2 synovial fluid lavage samples of TMJs of 2 asymptomatic served as normal controls referred from other data.
The concentrations of PGE₂were measured by use of PGE₂EIA system (Amersham®).
The following results were obtained :
1. In nine patients, the concentrations of PGE₂are lower after open reduction than before.
2. In three patients, the concentrations of PGE₂are higher after open reduction than before.
3. There was no statistical significant between the preoperative group and postoperative 7 days (p>0.05), but there as some difference between the two groups.
In conclusion, the results suggest that PGE₂probably does not play as important role in the harm of TMJ.
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